|
KMID : 0358920200470040446
|
|
Journal of the Korean Academy of Pedodontics
2020 Volume.47 No. 4 p.446 ~ p.453
|
|
|
Streptococcus Mutans Biofilm Inhibition Effect of Indocyanine Green and Near Infrared Diode Laser
|
|
Kim Yeo-Won
Park Ho-Won
Lee Ju-Hyun
Seo Hyun-Woo
Lee Si-Young
|
|
|
Abstract
|
|
|
|
The purpose of this study was to evaluate the effect of Indocyanine Green (ICG) and near-infrared (NIR) diode laser on Streptococcus mutans biofilms depending on ICG concentrations. S. mutans biofilms were formed on a Hydroxyapatite disk, and 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 mg/mL ICG solutions dissolved in sterile distilled water and a NIR diode laser having a power of 300 mW and a wavelength of 808 nm were applied to the biofilms. The temperature changes of the biofilm surface according to the concentrations of the ICG solution were measured using a 1-channel thermocouple thermometer. Compared to the control group, in the groups with only the 3.0, 4.0, 5.0 mg/mL ICG solution application, and in the groups with the 1.0, 2.0, 3.0, 4.0, 5.0 mg/mL ICG solution application and light irradiation, a statistically significant decrease in the bacterial counts were observed. The temperature increase according to the concentration of the ICG solutions was 9.53℃, 10.43℃, 11.40℃, 12.10℃, 12.67℃, and 13.63℃ in ICG solutions of 0.5, 1.0, 2.0, 3.0, 4.0, and 5.0 mg/mL respectively. This study presents the potential for clinical application of ICG and NIR diode lasers as a new method for preventing dental caries.
|
|
|
KEYWORD
|
|
|
Indocyanine Green, Near Infrared Diode laser, Streptococcus mutans, Biofilm, Photodynamic therapy, Photothermal therapy
|
|
|
FullTexts / Linksout information
|
|
  
|
|
|
Listed journal information
|
|
|
|